Smoking is a risk factor for multiple sclerosis.

@article{Riise2003SmokingIA,
  title={Smoking is a risk factor for multiple sclerosis.},
  author={Trond Riise and Monica Wammen Nortvedt and Alberto Ascherio},
  journal={Neurology},
  year={2003},
  volume={61 8},
  pages={
          1122-4
        }
}
The authors determined the relationship between tobacco smoking and the risk of developing multiple sclerosis (MS) in a general population of 22,312 individuals living in Hordaland, Norway in 1997. A total of 87 individuals reported having developed MS. The risk of MS was higher among smokers than among never-smokers (rate ratio 1.81, 95% CI 1.1 to 2.9; p = 0.014). Studies on how smoking interacts with disease onset may contribute to determining the causal agents of this disease. 

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