Smoking in schizophrenia: recent findings about an old problem.

@article{agud2019SmokingIS,
  title={Smoking in schizophrenia: recent findings about an old problem.},
  author={Marina {\vS}agud and Alma Mihaljevi{\'c} Pele{\vs} and Nela Pivac},
  journal={Current Opinion in Psychiatry},
  year={2019}
}
PURPOSE OF REVIEW Recent epidemiology, biological and clinical findings correlate high cigarette consumption in patients with schizophrenia, impeding both treatment strategies and the effectiveness of antipsychotics. RECENT FINDINGS New data suggests that despite world-wide efforts to curb cigarette consumption, smoking in patients with schizophrenia was still high. Recent reports could not confirm earlier findings regarding smoking's beneficial effects on cognitive dysfunction, however, the… 
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References

SHOWING 1-10 OF 80 REFERENCES
Smoking in Schizophrenia: an Updated Review.
TLDR
There is no consistent evidence of favorable effects of nicotine on symptoms in schizophrenia, but the evidence of detrimental effects of smoking on general health is highly consistent.
Cigarette smoking and schizophrenia: a specific clinical and therapeutic profile? Results from the FACE-Schizophrenia cohort
Neurobiological Determinants of Tobacco Smoking in Schizophrenia
TLDR
Tobacco smoking may alleviate specific symptoms associated with schizophrenia, and understanding the neurobiological underpinnings and psychosocial determinants of this comorbidity may better explain these potential beneficial effects, while also providing important insights into effective treatments for smoking cessation.
Tobacco smoking and its association with cognition in first episode psychosis patients
Assessment of the Association Between Cigarette Smoking and Cognitive Performance in Patients With Schizophrenia-Spectrum Disorders: A Case-Control Study
TLDR
It is shown that cigarette smoking is related to worse delayed memory performance in schizophrenia patients as well as deficits of immediate memory, visuospatial/constructional functions, and global cognition in controls.
Tobacco smoking is associated with antipsychotic medication, physical aggressiveness, and alcohol use disorder in schizophrenia: results from the FACE-SZ national cohort
TLDR
Further longitudinal studies are needed to confirm the potential efficacy of second generation antipsychotics (SGAs) on tobacco use in schizophrenia and to develop effective strategies for tobacco cessation in this population.
Cortisol in schizophrenia: No association with tobacco smoking, clinical symptoms or antipsychotic medication
Smoking Rates and Number of Cigarettes Smoked per Day in Schizophrenia: A Large Cohort Meta-Analysis in a Japanese Population
TLDR
Schizophrenia patients are approximately 2 times more likely to smoke than the general population and healthy controls based on data collected over a decade in Japan.
The effects of tobacco smoking, and prenatal tobacco smoke exposure, on risk of schizophrenia: a systematic review and meta-analysis.
TLDR
The findings suggest smoking, and prenatal smoke exposure, may be an independent risk factor for schizophrenia, and these results may have important public health implications for decreasing the incidence of schizophrenia.
Cigarette Smoking by Patients With Serious Mental Illness, 1999-2016: An Increasing Disparity.
TLDR
The prevalence of smoking has remained alarmingly high among individuals with schizophrenia and bipolar disorder, and the disparity with those without psychiatric disorders and with the general population is increasing.
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