Smoking in Patients Receiving Psychotropic Medications

@article{Desai2001SmokingIP,
  title={Smoking in Patients Receiving Psychotropic Medications},
  author={H. Desai and J. Seabolt and M. Jann},
  journal={CNS Drugs},
  year={2001},
  volume={15},
  pages={469-494}
}
  • H. Desai, J. Seabolt, M. Jann
  • Published 2001
  • Medicine
  • CNS Drugs
  • Many psychiatric patients smoke, and are believed to be heavier smokers than those without psychiatric disorders. Cigarette smoking is one of the environmental factors that contributes to interindividual variations in response to an administered drug. Polycyclic aromatic hydrocarbons (PAHs) present in cigarette smoke induce hepatic aryl hydrocarbon hydroxylases, thereby increasing metabolic clearance of drugs that are substrates for these enzymes. PAHs have been shown to induce 3 hepatic… CONTINUE READING
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