Smoking habit, immune suppression, oral contraceptive use, and hormone replacement therapy use and cervical carcinogenesis: a review of the literature

@article{Gadducci2011SmokingHI,
  title={Smoking habit, immune suppression, oral contraceptive use, and hormone replacement therapy use and cervical carcinogenesis: a review of the literature},
  author={A. Gadducci and C. Barsotti and S. Cosio and L. Domenici and A. Riccardo Genazzani},
  journal={Gynecological Endocrinology},
  year={2011},
  volume={27},
  pages={597 - 604}
}
  • A. Gadducci, C. Barsotti, +2 authors A. Riccardo Genazzani
  • Published 2011
  • Medicine
  • Gynecological Endocrinology
  • High-risk human papillomaviruses (HPVs) are involved in the etiopathogenesis of cervical intraepithelial neoplasia (CIN) and cervical cancer. After taking HPV into account, smoking habit appears to be the most significant environmental risk factor, and the risk of this malignancy increases significantly with intensity and duration of smoking. Women with human immunodeficiency virus (HIV) infection experience a higher incidence of CIN and invasive cervical cancer. Among HIV+ women, the highly… CONTINUE READING
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