Smoking as a trigger for inflammatory rheumatic diseases.

  title={Smoking as a trigger for inflammatory rheumatic diseases.},
  author={Lars Klareskog and Leonid Padyukov and Lars Alfredsson},
  journal={Current opinion in rheumatology},
  volume={19 1},
PURPOSE OF REVIEW This review has two purposes: to describe the known effects of cigarette smoking on the development of inflammatory rheumatic diseases, in particular rheumatoid arthritis and systemic lupus erythematosus, and to review recent research aimed at understanding the mechanisms by which smoking may interact with genes and immunity in triggering these diseases. RECENT FINDINGS Large case-control studies as well as cohort studies have demonstrated that cigarette smoking is a risk… CONTINUE READING


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