Smoking and multiple sclerosis: evidence for latitudinal and temporal variation

@article{OGorman2014SmokingAM,
  title={Smoking and multiple sclerosis: evidence for latitudinal and temporal variation},
  author={Cullen O’Gorman and Simon A. Broadley},
  journal={Journal of Neurology},
  year={2014},
  volume={261},
  pages={1677-1683}
}
There is growing evidence for the role of smoking in the aetiology of multiple sclerosis. We have expanded existing meta-analyses and further explored the roles of study design, gender, latitude and year of study with regression modelling. We have found a consistent association between smoking and MS with an odds ratio of approximately 1.5, with males at higher risk. This finding is independent of study design. However, latitude and year of study may have unexpected influence. Smoking appeared… CONTINUE READING
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