Smoking alters the antigenicity and infectivity of Porphyromonas gingivalis

  title={Smoking alters the antigenicity and infectivity of Porphyromonas gingivalis},
  author={Iris Zeller and Justin A. Hutcherson and Richard J Lamont and Donald R Demuth and Pinar Gumus and Nejat Nizam and Nurcan Buduneli and David J. Scott},
Background Cigarette smokers are more susceptible to periodontal diseases and are more likely to be infected with Porphyromonas gingivalis than non-smokers. Furthermore, smoking is known to alter the expression of P. gingivalis surface components and to compromise IgG generation. The aim of this study was to evaluate if the overall IgG response to P. gingivalis is suppressed in smokers in vivo and if previously established in vitro tobaccoinduced phenotypic P. gingivalis changes would be… CONTINUE READING

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