291 Citations
Nicotine and Parkinson's disease: Implications for therapy
- Psychology, BiologyMovement disorders : official journal of the Movement Disorder Society
- 2008
Observations suggest that nicotine or CNS selective nicotinic receptor ligands hold promise for Parkinson's disease therapy to reduce disease progression, improve symptoms, and/or decrease levodopa‐induced dyskinesias.
Can nicotine be used medicinally in Parkinson’s disease?
- Biology, PsychologyExpert review of clinical pharmacology
- 2011
Together, data suggest that nicotine or nicotinic receptor drugs have therapeutic potential for Parkinson’s disease, although the specific treatment regimens remain to be determined.
Nicotine from cigarette smoking and diet and Parkinson disease: a review
- Biology, PsychologyTranslational Neurodegeneration
- 2017
As a small amount of nicotine can saturate a substantial portion of nicotine receptors in the brain, nicotine from other sources, such as diet, could be a promising therapeutic substance for protection against PD.
Nicotinic receptors as CNS targets for Parkinson's disease.
- Biology, PsychologyBiochemical pharmacology
- 2007
Neuropathology of cigarette smoking
- Medicine, PsychologyActa Neuropathologica
- 2013
This work aims to summarize what is known about the neuropathology of cigarette smoking and, in particular, its implications for neurodegenerative diseases.
Nicotine as a potential neuroprotective agent for Parkinson's disease
- Biology, PsychologyMovement disorders : official journal of the Movement Disorder Society
- 2012
Findings suggest that nicotine and nAChR drugs represent promising therapeutic agents for the management of Parkinson's disease.
Smoking, nicotine and neuropsychiatric disorders
- Psychology, MedicineNeuroscience & Biobehavioral Reviews
- 2010
Preclinical Evidence for a Role of the Nicotinic Cholinergic System in Parkinson’s Disease
- Biology, PsychologyNeuropsychology Review
- 2015
Preclinical findings supporting the idea that nicotinic receptors are valuable therapeutic targets for PD are reviewed.
Nongenetic causes of Parkinson's disease.
- MedicineJournal of neural transmission. Supplementum
- 2006
Cigarette smoking, use of coffee/caffeine, and non-steroidal antiinflammatory drugs (NSAIDs) all appear to lower risk of PD, while dietary lipid and milk consumption, high caloric intake, and head trauma may increase risk.
Nicotine neuroprotection against nigrostriatal damage: importance of the animal model.
- Biology, PsychologyTrends in pharmacological sciences
- 2007
References
SHOWING 1-10 OF 98 REFERENCES
Nicotine and nicotinic receptors; relevance to Parkinson's disease.
- Biology, PsychologyNeurotoxicology
- 2002
The effects of nicotine on Parkinson's disease.
- Psychology, BiologyBrain and cognition
- 2000
Preliminary analysis shows improvements after acute nicotine in several areas of cognitive performance, particularly measures such as reaction time, central processing speed, and decreased tracking error, and improvements were seen in several motor measures suggesting improved extrapyramidal functioning.
Cigarette smoking and protection from Parkinson's disease
- Psychology, MedicineNeurology
- 1995
A protective association of cigarette smoking for Parkinson's disease may constitute an important etiologic clue.
Smoking and Parkinson's disease.
- Medicine, PsychologyJournal of neurology, neurosurgery, and psychiatry
- 1982
The negative association between Parkinson's disease and smoking is confirmed and is independent of other associated factors, and the positive correlation of degenerative vascular disease with smoking is further evidence that arteriosclerosis is not involved in the causation of Parkinson's Disease.
Effects of smoking in patients with early-onset Parkinson's disease
- Medicine, PsychologyJournal of the Neurological Sciences
- 1993
Beneficial effects of nicotine and cigarette smoking: the real, the possible and the spurious.
- MedicineBritish medical bulletin
- 1996
Preliminary data suggest that there may be inverse associations of smoking with uterine fibroids and endometriosis, and protective effects on hypertensive disorders and vomiting of pregnancy are likely, and evidence is growing that cigarette smoking and nicotine may prevent or ameliorate Parkinson's disease, and could do so in Alzheimer's dementia.
The environment and Parkinson's disease: is the nigrostriatal system preferentially targeted by neurotoxins?
- Biology, PsychologyThe Lancet. Neurology
- 2003
Similarities between clinical and experimental findings, such as the role of pesticide exposure as a potential environmental risk factor, highlight the importance of a multidisciplinary approach to the aetiology of PD.
The environment and Parkinson's disease: is the nigrostriatal system preferentially targeted by neurotoxins?
- BiologyThe Lancet Neurology
- 2003
Tobacco leaf, smoke and smoking, MAO inhibitors, Parkinson's disease and neuroprotection; are there links?
- BiologyNeurotoxicology
- 2004