Smoke inhalation injury and the effect of carbon monoxide in the sheep model.

  title={Smoke inhalation injury and the effect of carbon monoxide in the sheep model.},
  author={Takeshi Shimazu and Hisashi Ikeuchi and Gene B. Hubbard and P C Langlinais and Arthur D. Mason and Basil A. Pruitt},
  journal={The Journal of trauma},
  volume={30 2},
The role of carbon monoxide (CO) in causing the physiologic and anatomic changes characteristic of smoke inhalation injury was evaluated in 34 sheep. The smoke-exposed group received a dose of smoke known to produce mild inhalation injury. The CO group received a pure gas mixture that contained concentrations of oxygen, carbon dioxide, and CO similar to those in the smoke. Cardiopulmonary function was measured immediately after exposure, and 24 and 72 hours after exposure. The CO group showed a… CONTINUE READING

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