Smallpox virus plaque phenotypes: genetic, geographical and case fatality relationships.

@article{Olson2009SmallpoxVP,
  title={Smallpox virus plaque phenotypes: genetic, geographical and case fatality relationships.},
  author={Victoria A. Olson and Kevin L. Karem and Scott K. Smith and Christine Marie Hughes and Inger K. Damon},
  journal={The Journal of general virology},
  year={2009},
  volume={90 Pt 4},
  pages={792-8}
}
Smallpox (infection with Orthopoxvirus variola) remains a feared illness more than 25 years after its eradication. Historically, case-fatality rates (CFRs) varied between outbreaks (<1 to approximately 40 %), the reasons for which are incompletely understood. The extracellular enveloped virus (EEV) form of orthopoxvirus progeny is hypothesized to… CONTINUE READING