Smallpox vaccines for biodefense: need and feasibility

  title={Smallpox vaccines for biodefense: need and feasibility},
  author={A. Artenstein and J. Grabenstein},
  journal={Expert Review of Vaccines},
  pages={1225 - 1237}
  • A. Artenstein, J. Grabenstein
  • Published 2008
  • Medicine
  • Expert Review of Vaccines
  • Smallpox, eradicated as a cause of natural disease through an intensive global effort in the later part of the 20th Century, has resurfaced as a possible agent of bioterrorism. For this reason, there is renewed interest in smallpox vaccines. Live vaccinia virus, an orthopoxvirus related to smallpox, has a long and successful clinical track record as an effective smallpox vaccine; however, its use is associated with uncommon yet serious adverse events. This has led to a surge of recent research… CONTINUE READING

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