Smallpox and live-virus vaccination in transplant recipients.

  title={Smallpox and live-virus vaccination in transplant recipients.},
  author={Jay A Fishman},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  volume={3 7},
  • Jay A Fishman
  • Published 2003 in
    American journal of transplantation : official…
Recent bioterrorism raises the specter of reemergence of smallpox as a clinical entity. The mortality of variola major infection ('typical smallpox') was approximately 30% in past outbreaks. Programs for smallpox immunization for healthcare workers have been proposed. Atypical forms of smallpox presenting with flat or hemorrhagic skin lesions are most common in individuals with immune deficits with historic mortality approaching 100%. Smallpox vaccination, even after exposure, is highly… CONTINUE READING