Smaller infarct after preconditioning does not predict extent of early functional improvement of reperfused heart.

@article{Cohen1999SmallerIA,
  title={Smaller infarct after preconditioning does not predict extent of early functional improvement of reperfused heart.},
  author={Michael V. Cohen and X M Yang and James M. Downey},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={1999},
  volume={277 5},
  pages={H1754-H1761}
}
We evaluated the ability of ischemic preconditioning to restore function to salvaged myocardium in rabbits. Although ischemic preconditioning reduces infarct size, few investigators studying recovery of function after coronary occlusions lasting ≥30 min have reported any mechanical benefit in preconditioned hearts. However, because myocardial function was seldom evaluated beyond 5 h after reperfusion stunning may have masked the benefit. Accordingly, rabbits were chronically instrumented with a… CONTINUE READING

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