Small solutions for big problems: the application of nanoparticles to brain tumor diagnosis and therapy.

@article{Orringer2009SmallSF,
  title={Small solutions for big problems: the application of nanoparticles to brain tumor diagnosis and therapy.},
  author={Daniel A. Orringer and Yong Eui Koo and Tongkai Chen and Raoul Kopelman and Oren Sagher and Martin A. Philbert},
  journal={Clinical pharmacology and therapeutics},
  year={2009},
  volume={85 5},
  pages={531-4}
}
Why NaNoparticles? One of the key reasons that nanoparticles have promise in the treatment of cancer is that they can be targeted to tumors through antigen-dependent (specific) or antigen-independent (nonspecific) mechanisms. Specific targeting relies on the interaction of antigens on the surface of nanoparticles with tumor cell receptors. A variety of molecules including peptides (arginine– glycine–aspartic acid,1 F3,2 and chlorotoxin3), cytokines (interleukin-134), drugs (methotrexate5… CONTINUE READING

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