Small proteins can no longer be ignored.

  title={Small proteins can no longer be ignored.},
  author={Gisela Storz and Yuri I. Wolf and Kumaran S Ramamurthi},
  journal={Annual review of biochemistry},
Small proteins, here defined as proteins of 50 amino acids or fewer in the absence of processing, have traditionally been overlooked due to challenges in their annotation and biochemical detection. In the past several years, however, increasing numbers of small proteins have been identified either through the realization that mutations in intergenic regions are actually within unannotated small protein genes or through the discovery that some small, regulatory RNAs encode small proteins. These… CONTINUE READING
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