Small plasmids carrying vga(A) or vga(C) genes mediate resistance to lincosamides, pleuromutilins and streptogramin A antibiotics in methicillin-resistant Staphylococcus aureus ST398 from swine.

@article{Kadlec2010SmallPC,
  title={Small plasmids carrying vga(A) or vga(C) genes mediate resistance to lincosamides, pleuromutilins and streptogramin A antibiotics in methicillin-resistant Staphylococcus aureus ST398 from swine.},
  author={Kristina Kadlec and Constança Pomba and Natacha Couto and Stefan Schwarz},
  journal={The Journal of antimicrobial chemotherapy},
  year={2010},
  volume={65 12},
  pages={2692-3}
}
Sir, Methicillin-resistant Staphylococcus aureus (MRSA) isolates of the sequence type ST398 have been identified recently from cases of exudative epidermitis in swine, but also as colonizers of apparently healthy swine in Portugal. A considerable number of these isolates displayed an unusual resistance phenotype, namely resistance to the lincosamide clindamycin, but susceptibility to the macrolide erythromycin. Since the genetic basis of this resistance phenotype is unknown, we selected five… CONTINUE READING

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