Small nuclear RNAs and mRNAs: linking RNA processing and transport to spinal muscular atrophy.

Abstract

The splicing of pre-mRNA by the spliceosome is a characteristic feature of eukaryotic cells, dependent on a group of snRNPs (small nuclear ribonucleoproteins). These splicing snRNPs have a complex assembly pathway involving multiple steps that take place in different regions of the cell, which is reflected in their complex subcellular distribution. Vital to… (More)
DOI: 10.1042/BST20120016

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