Small molecules in cellular reprogramming and differentiation.

  title={Small molecules in cellular reprogramming and differentiation.},
  author={Xu Yuan and Wenlin Wendy Li and Sheng Ding},
  journal={Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques},
Recent advances in somatic cell reprogramming and directed differentiation make it possible to generate patient-specific pluripotent cells and further derive functional tissue-specific cells for biomedical research and future therapies. Chemical compounds targeting enzymes or signaling proteins are powerful tools to regulate and reveal complex cellular processes and have been identified and applied to controlling cell fate and function, including stem cell maintenance, differentiation, and… CONTINUE READING

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