Small molecule inhibitors of mitochondrial division: tools that translate basic biological research into medicine.


Mitochondria do not exist as discrete static entities; rather, mitochondria form a network that continuously moves, divides, and fuses. The structure of this dynamic network is in part maintained by a balance of division and fusion events (Hoppins et al., 2007). The ratio of division to fusion events that defines a proper balance is not universal but varies… (More)
DOI: 10.1016/j.chembiol.2010.05.016