Small molecule ambient mass spectrometry imaging by infrared laser ablation metastable-induced chemical ionization.

@article{Galhena2010SmallMA,
  title={Small molecule ambient mass spectrometry imaging by infrared laser ablation metastable-induced chemical ionization.},
  author={Asiri S. Galhena and Glenn A. Harris and Leonard Nyadong and Kermit K. Murray and Facundo M. Fern{\'a}ndez},
  journal={Analytical chemistry},
  year={2010},
  volume={82 6},
  pages={
          2178-81
        }
}
Presented here is a novel ambient ion source termed infrared laser ablation metastable-induced chemical ionization (IR-LAMICI). IR-LAMICI integrates IR laser ablation and direct analysis in real time (DART)-type metastable-induced chemical ionization for open air mass spectrometry (MS) ionization. The ion generation in the IR-LAMICI source is a two step process. First, IR laser pulses impinge the sample surface ablating surface material. Second, a portion of ablated material reacts with the… CONTINUE READING

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