Small longitudinal study of serum anticholinergic activity and cognitive change in community-dwelling older adults.

@article{Kashyap2015SmallLS,
  title={Small longitudinal study of serum anticholinergic activity and cognitive change in community-dwelling older adults.},
  author={Mandavi Kashyap and Benoit H. Mulsant and Cara Tannenbaum},
  journal={The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry},
  year={2015},
  volume={23 3},
  pages={
          326-9
        }
}
OBJECTIVE The discriminative ability of serum anticholinergic activity (SAA) to differentiate between older individuals with stable versus deteriorating cognition remains undetermined. We examined the relationship between SAA changes, the presence or absence of a mild neurocognitive disorder, age and anticholinergic medication over a one-year time period. METHODS SAA at baseline and one-year follow-up was measured for 121 older adults without dementia. Participants were classified at both… CONTINUE READING
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