Small intestinal growth caused by feeding red kidney bean phytohemagglutinin lectin to rats.

@article{Banwell1993SmallIG,
  title={Small intestinal growth caused by feeding red kidney bean phytohemagglutinin lectin to rats.},
  author={John G. Banwell and Richard Howard and Iqbal Kabir and Thomas Edward Adrian and Robert H Diamond and Carlos Abramowsky},
  journal={Gastroenterology},
  year={1993},
  volume={104 6},
  pages={1669-77}
}
BACKGROUND Plant lectins are present in significant quantity in a variety of food sources. The aim of this study was to determine if they stimulated growth of the intestine. METHODS Germ-free and conventional rats were pair fed purified phytohemagglutinin lectin (PHA) or equivalent casein in a fully nutritious diet. PHA was instilled into in situ jejunal and ileal loops. Organ weight, length, DNA, protein content, morphometry, and [3H]thymidine uptake into jejunal crypt cells were measured… CONTINUE READING

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