Small integrin-binding proteins as serum markers for prostate cancer detection.

  title={Small integrin-binding proteins as serum markers for prostate cancer detection.},
  author={Alka Jain and Dianalee A McKnight and Larry W. Fisher and Elizabeth B. Humphreys and Leslie A. Mangold and Alan W. Partin and Neal S. Fedarko},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  volume={15 16},
PURPOSE The small integrin-binding ligand N-linked glycoprotein (SIBLING) gene family includes bone sialoprotein (BSP), dentin matrix protein 1 (DMP1), dentin sialophosphoprotein (DSPP), matrix extracellular phosphoglycoprotein (MEPE), and osteopontin (OPN). Previous studies have separately reported elevated expression of BSP, OPN, or DSPP in prostate tumor paraffin sections. We hypothesized that SIBLINGs may be informative serum markers for subjects with prostate cancer. METHODS Expression… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 18 extracted citations


Publications referenced by this paper.
Showing 1-10 of 45 references

tality results from a randomized prostate - cancer screening trial

  • GL Andriole, RL Grubb, SS Buys
  • N Engl J Med
  • 2009

Similar Papers

Loading similar papers…