Small heat shock proteins and vasospasm in human umbilical artery smooth muscle.

@article{Brophy1997SmallHS,
  title={Small heat shock proteins and vasospasm in human umbilical artery smooth muscle.},
  author={Colleen Marie Brophy and Ashley D Beall and Sara Lamb and Mary Kathryne Dickinson and Darol Ware},
  journal={Biology of reproduction},
  year={1997},
  volume={57 6},
  pages={1354-9}
}
Human umbilical artery smooth muscle is uniquely refractory to cyclic nucleotide-dependent vasorelaxation. Small heat shock proteins (HSPs) have been implicated as contractile regulatory proteins. Thus, we hypothesized that alterations in the phosphorylation of small HSPs may contribute to human umbilical artery smooth muscle vasospasm. Physiologic… CONTINUE READING