Small heat shock proteins and protection against ischemic injury in cardiac myocytes.

@article{Martin1997SmallHS,
  title={Small heat shock proteins and protection against ischemic injury in cardiac myocytes.},
  author={Jody L Martin and Ruben Mestril and Randa Hilal-Dandan and Laurence L. Brunton and Wolfgang H. Dillmann},
  journal={Circulation},
  year={1997},
  volume={96 12},
  pages={4343-8}
}
BACKGROUND Overexpression of the inducible hsp70 protects against ischemic cardiac damage. However, it is unclear whether the small heat shock proteins hsp27 and alphaB-crystallin protect against ischemic injury. METHODS AND RESULTS Our aim was to examine whether the overexpression of hsp27 and alphaB-crystallin in neonatal and adult rat cardiomyocytes would protect against ischemic injury. Recombinant adenovirus expressing hsp27 or alphaB-crystallin under the control of the cytomegalovirus… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 139 extracted citations

Similar Papers

Loading similar papers…