Small heat shock protein 27 (Hsp27) expression is highly induced in rat myometrium during late pregnancy and labour.

@article{White2005SmallHS,
  title={Small heat shock protein 27 (Hsp27) expression is highly induced in rat myometrium during late pregnancy and labour.},
  author={Bryan Glover White and Selena Joy Williams and K Highmore and Daniel J MacPhee},
  journal={Reproduction},
  year={2005},
  volume={129 1},
  pages={
          115-26
        }
}
The underlying mechanisms that regulate uterine contractions during labour are still poorly understood. A candidate regulatory protein is heat shock protein 27 (Hsp27). It belongs to the small heat shock protein family and can regulate actin cytoskeleton dynamics, act as a chaperone, and may regulate contractile protein activation. As a result, we hypothesized that Hsp27 expression would be highly induced during late pregnancy and labour. Hsp27 mRNA expression was significantly elevated (P <0… CONTINUE READING

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