Small fiber neuropathy: is skin biopsy the holy grail?

Abstract

Small fiber neuropathy (SFN) is characterized by negative sensory symptoms (thermal and pinprick hypoesthesia) reflecting peripheral deafferentation and positive sensory symptoms and signs (burning pain, allodynia, hyperalgesia), which often dominate the clinical picture. In patients with pure SFN, clinical and neurophysiologic investigation do not show… (More)
DOI: 10.1007/s11892-012-0280-9

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