Small effect of dopamine release and no effect of dopamine depletion on [18F]fallypride binding in healthy humans.

@article{Cropley2008SmallEO,
  title={Small effect of dopamine release and no effect of dopamine depletion on [18F]fallypride binding in healthy humans.},
  author={Vanessa L. Cropley and Robert B. Innis and Pradeep J. Nathan and Amira K. Brown and Janet L Sangare and Alicja Lerner and Yong Hoon Ryu and Kelly E Sprague and Victor W. Pike and Masahiro Fujita},
  journal={Synapse},
  year={2008},
  volume={62 6},
  pages={399-408}
}
Molecular imaging has been used to estimate both drug-induced and tonic dopamine release in the striatum and most recently extrastriatal areas of healthy humans. However, to date, studies of drug-induced and tonic dopamine release have not been performed in the same subjects. This study performed positron emission tomography (PET) with [18F]fallypride in healthy subjects to assess (1) the reproducibility of [18F]fallypride and (2) both D-amphetamine-induced and alpha-methyl-p-tyrosine (AMPT… CONTINUE READING
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