Small cell lung carcinoma in a patient with Sotos syndrome: are genes at 3p21 involved in both conditions?

@article{Cole1992SmallCL,
  title={Small cell lung carcinoma in a patient with Sotos syndrome: are genes at 3p21 involved in both conditions?},
  author={Trevor R. P. Cole and Helen M Hughes and Mona Jeffreys and Geraint T. Williams and Muoi M. Arnold},
  journal={Journal of medical genetics},
  year={1992},
  volume={29 5},
  pages={338-41}
}
A 22 year old female with Sotos syndrome and a small cell lung carcinoma is described. This case is of interest not only because of the somatic growth pattern, atypical of Sotos syndrome, but also because of the association with a rare tumour. Of significance is the possible role of mutations at 3p21 in the aetiology of Sotos syndrome and tumour development. 

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