Small cell lung carcinoma cell line screen of etoposide/carboplatin plus a third agent


The SCLC combination screen examined a 9-point concentration response of 180 third agents, alone and in combination with etoposide/carboplatin. The predominant effect of adding a third agent to etoposide/carboplatin was additivity. Less than additive effects occurred frequently in SCLC lines sensitive to etoposide/carboplatin. In SCLC lines with little or… (More)
DOI: 10.1002/cam4.1131


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