Small-caliber heparin-coated ePTFE grafts reduce platelet deposition and neointimal hyperplasia in a baboon model.

@article{Lin2004SmallcaliberHE,
  title={Small-caliber heparin-coated ePTFE grafts reduce platelet deposition and neointimal hyperplasia in a baboon model.},
  author={Peter H Lin and Changyi Johnny Chen and Ruth Lee Bush and Q. -S. Yao and Alan B. Lumsden and Stephen R. Hanson},
  journal={Journal of vascular surgery},
  year={2004},
  volume={39 6},
  pages={1322-8}
}
PURPOSE Intimal hyperplasia and graft thrombosis are major causes of graft failure. Heparin prolongs graft patency and inhibits neointimal hyperplasia in animal models. The purpose of this study was to evaluate the effect of a heparin-coated expanded polytetrafluoroethylene (ePTFE) graft on platelet deposition and anastomotic neointimal hyperplasia after aortoiliac bypass grafting in a baboon model. METHODS Heparin-coated ePTFE grafts (4-mm diameter) were incorporated into exteriorized… CONTINUE READING

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