Small but versatile: the extraordinary functional and structural diversity of the β-grasp fold

@article{Burroughs2007SmallBV,
  title={Small but versatile: the extraordinary functional and structural diversity of the β-grasp fold},
  author={A. Maxwell Burroughs and Santhanam Balaji and Lakshminarayan M. Iyer and L. Aravind},
  journal={Biology Direct},
  year={2007},
  volume={2},
  pages={18 - 18}
}
The β-grasp fold (β-GF), prototyped by ubiquitin (UB), has been recruited for a strikingly diverse range of biochemical functions. These functions include providing a scaffold for different enzymatic active sites (e.g. NUDIX phosphohydrolases) and iron-sulfur clusters, RNA-soluble-ligand and co-factor-binding, sulfur transfer, adaptor functions in signaling, assembly of macromolecular complexes and post-translational protein modification. To understand the basis for the functional versatility… CONTINUE READING
54 Citations
138 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 54 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 138 references

Similar Papers

Loading similar papers…