Small-animal positron emission tomography as a tool for neuropharmacology.

  title={Small-animal positron emission tomography as a tool for neuropharmacology.},
  author={Sophie Lancelot and Luc Zimmer},
  journal={Trends in pharmacological sciences},
  volume={31 9},
Small-animal positron emission tomography (PET) is a preclinical imaging method that uses pharmacologically or biochemically active compounds labelled with short-lived positron-emitting radionuclides. This non-invasive nuclear medicine technique requiring animal-dedicated PET cameras (microPET) enables in vivo measurements of physiological processes, biochemical pathways and neurotransmitters. It therefore has a role in studying the pathophysiology and pharmacology of the brain. Moreover, there… CONTINUE READING
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