Small-angle scattering for structural biology--expanding the frontier while avoiding the pitfalls.

@article{Jacques2010SmallangleSF,
  title={Small-angle scattering for structural biology--expanding the frontier while avoiding the pitfalls.},
  author={David A Jacques and Jill Trewhella},
  journal={Protein science : a publication of the Protein Society},
  year={2010},
  volume={19 4},
  pages={642-57}
}
The last decade has seen a dramatic increase in the use of small-angle scattering for the study of biological macromolecules in solution. The drive for more complete structural characterization of proteins and their interactions, coupled with the increasing availability of instrumentation and easy-to-use software for data analysis and interpretation, is expanding the utility of the technique beyond the domain of the biophysicist and into the realm of the protein scientist. However, the absence… CONTINUE READING