Small angle X-ray scattering as a complementary tool for high-throughput structural studies.

@article{Grant2011SmallAX,
  title={Small angle X-ray scattering as a complementary tool for high-throughput structural studies.},
  author={Thomas D. Grant and Joseph R. Luft and Jennifer R. Wolfley and Hiro Tsuruta and Anne Martel and Gaetano T. Montelione and Edward H. Snell},
  journal={Biopolymers},
  year={2011},
  volume={95 8},
  pages={517-30}
}
Structural crystallography and nuclear magnetic resonance (NMR) spectroscopy are the predominant techniques for understanding the biological world on a molecular level. Crystallography is constrained by the ability to form a crystal that diffracts well and NMR is constrained to smaller proteins. Although powerful techniques, they leave many soluble, purified structurally uncharacterized protein samples. Small angle X-ray scattering (SAXS) is a solution technique that provides data on the size… CONTINUE READING