Small Sample Issues for Microarray-Based Classification

  title={Small Sample Issues for Microarray-Based Classification},
  author={Edward R. Dougherty},
  journal={Comparative and Functional Genomics},
  pages={28 - 34}
In order to study the molecular biological differences between normal and diseased tissues, it is desirable to perform classification among diseases and stages of disease using microarray-based gene-expression values. Owing to the limited number of microarrays typically used in these studies, serious issues arise with respect to the design, performance and analysis of classifiers based on microarray data. This paper reviews some fundamental issues facing small-sample classification… CONTINUE READING
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