Small RNAs promote mRNA stability to activate the synthesis of virulence factors.

Abstract

Although most bacterial small RNAs act to repress target mRNAs, some also activate messengers. The predominant mode of activation has been seen in 'anti-antisense' regulation whereby a small RNA prevents the formation of an inhibitory 5' mRNA structure that otherwise impairs translational initiation and protein synthesis. The translational activation might… (More)
DOI: 10.1111/j.1365-2958.2010.07428.x

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