Small RNAs couple embryonic developmental programs to gut microbes

@article{Ohno2020SmallRC,
  title={Small RNAs couple embryonic developmental programs to gut microbes},
  author={Hayao Ohno and Zhirong Bao},
  journal={bioRxiv},
  year={2020}
}
Maternal exposure to microbes and other environmental factors is known to induce adaptive changes in the progeny, but little is understood about how development of the progeny is changed. We show that Caenorhabditis elegans undergoes additional embryonic cell divisions in response to maternal gut microbes such as one producing the biopolymer γ-poly-DL-glutamic acid. The divisions coincide with anatomical changes including left-right asymmetric cell alignment, doubling the association between… Expand
1 Citations
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