Small RNAs as Guardians of the Genome

@article{Malone2009SmallRA,
  title={Small RNAs as Guardians of the Genome},
  author={Colin D. Malone and Gregory J Hannon},
  journal={Cell},
  year={2009},
  volume={136},
  pages={656-668}
}
Transposons populate the landscape of all eukaryotic genomes. Often considered purely genomic parasites, transposons can also benefit their hosts, playing roles in gene regulation and in genome organization and evolution. Peaceful coexistence with mobile elements depends upon adaptive control mechanisms, since unchecked transposon activity can impact long-term fitness and acutely reduce the fertility of progeny. Here, we review the conserved roles played by small RNAs in the adaptation of… CONTINUE READING
Highly Influential
This paper has highly influenced 16 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 342 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 142 references

Similar Papers

Loading similar papers…