Small RNA expression and strain specificity in the rat

  title={Small RNA expression and strain specificity in the rat},
  author={Sam E V Linsen and Elzo de Wit and Ewart de Bruijn and Edwin Cuppen},
  booktitle={BMC Genomics},
Digital gene expression (DGE) profiling has become an established tool to study RNA expression. Here, we provide an in-depth analysis of small RNA DGE profiles from two different rat strains (BN-Lx and SHR) from six different rat tissues (spleen, liver, brain, testis, heart, kidney). We describe the expression patterns of known and novel micro (mi)RNAs and piwi-interacting (pi)RNAs. We confirmed the expression of 588 known miRNAs (54 in antisense orientation) and identified 56 miRNAs homologous… CONTINUE READING


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