Small RNA Modules Confer Different Stabilities and Interact Differently with Multiple Targets

@inproceedings{Andrade2013SmallRM,
  title={Small RNA Modules Confer Different Stabilities and Interact Differently with Multiple Targets},
  author={Jos{\'e} M Andrade and V{\^a}nia Pobre and Cec{\'i}lia M Arraiano},
  booktitle={PloS one},
  year={2013}
}
Bacterial Hfq-associated small regulatory RNAs (sRNAs) parallel animal microRNAs in their ability to control multiple target mRNAs. The small non-coding MicA RNA represses the expression of several genes, including major outer membrane proteins such as ompA, tsx and ecnB. In this study, we have characterised the RNA determinants involved in the stability of MicA and analysed how they influence the expression of its targets. Site-directed mutagenesis was used to construct MicA mutated forms. The… CONTINUE READING
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Evidence for an autonomous 5' target recognition domain in an Hfq-associated small RNA.

Proceedings of the National Academy of Sciences of the United States of America • 2010
View 4 Excerpts
Highly Influenced

Mfold web server for nucleic acid folding and hybridization prediction

Nucleic Acids Research • 2003
View 6 Excerpts
Highly Influenced

Comparative profiling of Pseudomonas aeruginosa strains reveals differential expression of novel unique and conserved small RNAs

S Ferrara, M Brugnoli, A De Bonis, F Righetti, F Delvillani
PLoS One • 2012
View 1 Excerpt