Small RNA: can RNA interference be exploited for therapy?

@article{Wall2003SmallRC,
  title={Small RNA: can RNA interference be exploited for therapy?},
  author={Nathan R. Wall and Yang Shi},
  journal={The Lancet},
  year={2003},
  volume={362},
  pages={1401-1403}
}
CONTEXT RNA interference (RNAi) is the sequence-specific gene-silencing induced by double-stranded RNA (dsRNA), and gives information about gene function quickly, easily, and inexpensively. The use of RNAi for genetic-based therapies is widely studied, especially in viral infections, cancers, and inherited genetic disorders. RNAi has been used to make tissue-specific knockdown mice for studying gene function in a whole animal. Combined with genomics data, RNAi-directed gene-silencing could… Expand
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