Small Molecule Inhibitors Targeting Activator Protein 1 (AP-1)

@inproceedings{Ye2014SmallMI,
  title={Small Molecule Inhibitors
Targeting Activator Protein
1 (AP-1)},
  author={Na Ye and Ye Ding and Christopher T Wild and Qiang Shen and Jia Zhou},
  booktitle={Journal of medicinal chemistry},
  year={2014}
}
Activator protein 1 (AP-1) is a pivotal transcription factor that regulates a wide range of cellular processes including proliferation, apoptosis, differentiation, survival, cell migration, and transformation. Accumulating evidence supports that AP-1 plays an important role in several severe disorders including cancer, fibrosis, and organ injury, as well as inflammatory disorders such as asthma, psoriasis, and rheumatoid arthritis. AP-1 has emerged as an actively pursued drug discovery target… CONTINUE READING
20 Citations
98 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 98 references

Similar Papers

Loading similar papers…