Small-Cell Lung Carcinoma Nicotine Stimulates a Serotonergic Autocrine Loop in Human

Abstract

Small-cell lung carcinoma cells express different plasma membrane im .n um acetylcholine receptor subtypes. We have now found that inter acting with these receptors (-)-nicotine induces a dose-dependent and stereoselective release of [3H]serotonin which is dependent on external calcium and blocked by the specific ganglionic nicotinic antagonist nice… (More)

Topics

4 Figures and Tables

Cite this paper

@inproceedings{Cattaneo2006SmallCellLC, title={Small-Cell Lung Carcinoma Nicotine Stimulates a Serotonergic Autocrine Loop in Human}, author={Maria Grazia Cattaneo and Agnese Codignola and Lucia Maria Vicentini and Francesco Clementi and Emanuele Sher}, year={2006} }