Small, medium but not large arteries are involved in digital ulcers associated with systemic sclerosis.

@article{Assou2016SmallMB,
  title={Small, medium but not large arteries are involved in digital ulcers associated with systemic sclerosis.},
  author={Linda A{\"i}ssou and Christophe Meune and J{\'e}r{\^o}me Avouac and Marine Meunier and Muriel Elha{\"i} and Emmanuel Sorbets and Andr{\'e} Kahan and Yannick Allanore},
  journal={Joint, bone, spine : revue du rhumatisme},
  year={2016},
  volume={83 4},
  pages={444-7}
}
OBJECTIVE Digital ulcers (DU) are a burden in systemic sclerosis (SSc). Microangiopathy is a cardinal feature of SSc that plays a critical role in the development of DU. However, whether injury of medium or large vessels also contributes to DU in SSc remains controversial. METHODS To measure concomitantly in SSc patients with and without active DU: (i) the Augmentation Index of the reflected wave (Aix_75) by radial applanation tonometry, an index of small and medium arterial function; (II… CONTINUE READING