Smad2 and Smad3 cooperate and antagonize simultaneously in vertebrate neurogenesis.

@article{Miguez2013Smad2AS,
  title={Smad2 and Smad3 cooperate and antagonize simultaneously in vertebrate neurogenesis.},
  author={David G. Miguez and Estel Gil-Gui{\~n}{\'o}n and Sebasti{\'a}n Pons and Elisa Mart{\'i}},
  journal={Journal of cell science},
  year={2013},
  volume={126 Pt 23},
  pages={5335-43}
}
The transforming growth factor beta (TGF-β) pathway plays key roles in development and cancer. TGF-β signaling converges on the Smad2 and Smad3 effectors, which can either cooperate or antagonize to regulate their transcriptional targets. Here we performed in vivo and in silico experiments to study how such cooperativity and antagonism might function during… CONTINUE READING
  • Blog articles referencing this paper

  • Presentations referencing similar topics