Smad 3 and PKC mediate TGF-1-induced collagen I expression in human mesangial cells

@inproceedings{Runyan2003Smad3A,
  title={Smad 3 and PKC mediate TGF-1-induced collagen I expression in human mesangial cells},
  author={Constance E. Runyan and H. William Schnaper and A M Poncelet},
  year={2003}
}
Runyan, Constance E., H. William Schnaper, and Anne-Christine Poncelet. Smad3 and PKC mediate TGF1-induced collagen I expression in human mesangial cells. Am J Physiol Renal Physiol 285: F413–F422, 2003. First published May 20, 2003; 10.1152/ajprenal.00082.2003.— Transforming growth factor (TGF)has been associated with fibrogenesis in clinical studies and animal models. We previously showed that Smad3 promotes COL1A2 gene activation by TGF1 in human mesangial cells. In addition to the Smad… CONTINUE READING