Smacoviridae: a new family of animal-associated single-stranded DNA viruses

  title={Smacoviridae: a new family of animal-associated single-stranded DNA viruses},
  author={A. Varsani and M. Krupovic},
  journal={Archives of Virology},
  • A. Varsani, M. Krupovic
  • Published 2018
  • Biology, Medicine
  • Archives of Virology
  • Smacoviruses have small (∼2.3-2.9 kb), circular single-stranded DNA genomes encoding rolling circle replication-associated proteins (Rep) and unique capsid proteins. Although smacoviruses are prevalent in faecal matter of various vertebrates, including humans, none of these viruses have been cultured thus far. Smacoviruses display ∼45% genome-wide sequence diversity, which is very similar to that found within other families of circular Rep-encoding single-stranded (CRESS) DNA viruses, including… CONTINUE READING

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