Sm-ChIPi: Single-Molecule Chromatin Immunoprecipitation Imaging.

  title={Sm-ChIPi: Single-Molecule Chromatin Immunoprecipitation Imaging.},
  author={Roubina Tatavosian and Xiaojun Ren},
  journal={Methods in molecular biology},
Epigenetic complexes regulate chromatin dynamics via binding to and assembling on chromatin. However, the mechanisms of chromatin binding and assembly of epigenetic complexes within cells remain incompletely understood, partly due to technical challenges. Here, we present a new approach termed single-molecule chromatin immunoprecipitation imaging (Sm-ChIPi… CONTINUE READING