SlyA regulates function of Salmonella pathogenicity island 2 (SPI-2) and expression of SPI-2-associated genes.

@article{Linehan2005SlyARF,
  title={SlyA regulates function of Salmonella pathogenicity island 2 (SPI-2) and expression of SPI-2-associated genes.},
  author={Sheena A Linehan and Anne Rytk{\"o}nen and Xiu-Jun Yu and Mei Feng Liu and David W. Holden},
  journal={Infection and immunity},
  year={2005},
  volume={73 7},
  pages={4354-62}
}
During the systemic phase of murine infection with Salmonella enterica serovar Typhimurium, bacterial virulence is correlated with the ability to grow and survive within host macrophages. Salmonella pathogenicity island 2 (SPI-2), encoding a type three secretion system, has emerged as an important contributor to Salmonella intracellular growth. SPI-2 mutants have been proposed to be more accessible than wild-type Salmonella to oxyradicals generated by the NADPH phagocyte oxidase. We performed… CONTINUE READING

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